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KIT Ligand Protein (KITLG)

Cette protéine Recombinant KIT Ligand est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN1097472

Aperçu rapide pour KIT Ligand Protein (KITLG) (ABIN1097472)

Antigène

Voir toutes KIT Ligand (KITLG) Protéines
KIT Ligand (KITLG)

Type de proteíne

Recombinant

Activité biologique

Active

Origine

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Humain

Source

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Escherichia coli (E. coli)

Application

Functional Studies (Func)

Pureté

> 95 % as determined by reducing SDS-PAGE.
  • Fonction

    Recombinant Human Stem Cell Factor/SCF/c-Kit Ligand

    Séquence

    MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA

    Attributs du produit

    Recombinant Human SCF (Stem Cell Factor) produced in E. coli is a single non-glycosylated polypeptide chain containing 165 amino acids with a molecular mass of 18.4 kDa.

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Commentaires

    Biological activity: ED50 is less than 2 ng/ml as determined by the dose-dependent stimulation of Human TF-1 cells.Specific Activity of 5.0 x 105 IU/mg.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.0.

    Conseil sur la manipulation

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Stock

    4 °C/-20 °C/-80 °C

    Stockage commentaire

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Date de péremption

    3 months
  • Antigène

    KIT Ligand (KITLG)

    Autre désignation

    scf

    Sujet

    Recombinant Human SCF: Stem Cell Factor is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.
    Alternative Names: Recombinant Human SCF, Kit Ligand, Mast Cell Growth Factor, MGF, Stem Cell Factor, SCF, c-Kit ligand, KITLG, MGF, SCF

    Poids moléculaire

    18.4 kDa

    UniProt

    P21583

    Pathways

    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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